Mirror lockup is a feature on most modern DSLR’s. I know that I became aware of it and neglected using it because it seemed like a lot and I didn’t understand exactly how it worked
This video does a great job of breaking it down. It talks about how you can do it with a remote/cable release or just use your cameras timer. It’s really pretty easy.
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You realize of course, if you’re talking bout 500px, those images are going to have to be resized for the web in which case “tack sharp” isn’t as much an issue anymore since you would be downsampling a bit. If the capture is so extremely soft and blurry that you can’t get decent sharpness from downsampling, then you have other problems to deal with.
I use the lockup and a cable release or the timer and have had great results. Always keep in mind however that besides keeping your camera perfectly still, your subject has to be perfectly still as well. If you have a slow shutter speed and some leaves on a tree move or anything else, you will get blurring.